(Clin Transl Med, 2021) in 24 older adults (aged 61-80) found that supplementation with GlyNAC (glycine 100 mg/kg/day + NAC 100 mg/kg/day, approximately 7 g each for a 70 kg person) for 16 weeks corrected glutathione deficiency and improved multiple hallmarks of aging including oxidative stress, mitochondrial dysfunction, inflammation, insulin resistance, endothelial dysfunction, body composition, exercise capacity, and cognition [10]
In skeletal muscle specifically, MOTS-c has been shown to enhance glucose transporter-4 (GLUT4) translocation to the cell surface, the molecular mechanism by which muscle cells absorb glucose from the bloodstream
Unexpected System-W ide Benefits Additional benefits beyond primary injury repair when using TB-500 include improved recovery from your workouts, enhanced sleep quality, and even better skin elasticity
Glutathione Glutathione (GSH), a tripeptide composed of glutamate, cysteine, and glycine, serves as a critical intracellular antioxidant that regulates redox homeostasis, detoxifies ROS, and modulates immune responses (Narayanankutty et al., 2019)